Dorianna Sandonà Selected Research

Sarcoglycans (beta Sarcoglycan)

1/2022	CFTR corrector C17 is effective in muscular dystrophy, in vivo proof of concept in LGMDR3.
3/2020	Combined Use of CFTR Correctors in LGMD2D Myotubes Improves Sarcoglycan Complex Recovery.
1/2018	Repairing folding-defective α-sarcoglycan mutants by CFTR correctors, a potential therapy for limb-girdle muscular dystrophy 2D.
7/2014	Unveiling the degradative route of the V247M α-sarcoglycan mutant responsible for LGMD-2D.
9/2009	Sarcoglycanopathies: molecular pathogenesis and therapeutic prospects.
7/2008	Inhibition of proteasome activity promotes the correct localization of disease-causing alpha-sarcoglycan mutants in HEK-293 cells constitutively expressing beta-, gamma-, and delta-sarcoglycan.
11/2005	Deficiency of alpha-sarcoglycan differently affects fast- and slow-twitch skeletal muscles.
7/2004	Characterization of the ATP-hydrolysing activity of alpha-sarcoglycan.

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Dorianna Sandonà Research Topics

Disease

5	Sarcoglycanopathies 03/2020 - 07/2008
4	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 01/2022 - 11/2005
3	Atrophy 01/2012 - 01/2008
2	Muscular Dystrophies (Muscular Dystrophy) 01/2022 - 07/2004
2	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 03/2020
2	Inborn Genetic Diseases (Disease, Hereditary) 07/2014 - 09/2009
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022
1	Ovarian Epithelial Carcinoma 01/2022
1	Neoplasms (Cancer) 01/2022
1	Isaacs Syndrome (Neuromyotonia) 11/2014
1	Muscular Atrophy (Muscle Atrophy) 01/2008
1	Fatigue 03/2006

Drug/Important Bio-Agent (IBA)

8	Sarcoglycans (beta Sarcoglycan)IBA 01/2022 - 07/2004
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2008
2	UbiquitinIBA 11/2014 - 01/2012
2	Ligases (Synthetase)IBA 07/2014 - 01/2012
1	Estrogens (Estrogen)FDA Link 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2014
1	Adenosine Triphosphatases (ATPase)IBA 11/2014
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 07/2014
1	Pharmaceutical PreparationsIBA 07/2014
1	EnzymesIBA 07/2014
1	LipidsIBA 03/2010
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 03/2010
1	Glycoproteins (Glycoprotein)IBA 09/2009
1	SphingosineIBA 01/2008
1	Protein Isoforms (Isoforms)IBA 03/2006
1	Homer Scaffolding Proteins (Homer 1)IBA 03/2006

Therapy/Procedure

4	Therapeutics 03/2020 - 07/2008
2	Denervation 03/2010 - 01/2008